Convenient modular method for affinity labeling (MoAL method) based on a catalytic amidation
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چکیده
منابع مشابه
Convenient modular method for affinity labeling (MoAL method) based on a catalytic amidation.
A modular methodology for affinity labeling, in which three essential elements generally constituting affinity probes are prepared separately as individual molecules, has been developed based on a catalytic amidation.
متن کاملConvenient modular method for affinity labeling (MoAL method) based on a catalytic amidationw
*KURAに登録されているコンテンツの利用については,著作権法に規定されている私的使用や引用などの範囲内で行ってください。 *著作権法に規定されている私的使用や引用などの範囲を超える利用を行う場合には,著作権者の許諾を得てください。ただし,著作権者 から著作権等管理事業者(学術著作権協会,日本著作出版権管理システムなど)に権利委託されているコンテンツの利用手続については ,各著作権等管理事業者に確認してください。 Title Convenient modular method for affinity labeling (MoAL method) based on a catalytic amidation Author(s) Kunishima, Munetaka; Nakanishi, Shuichi; Nishida, Jin; Tanaka, Hiroyuki; Morisa...
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We studied the specific labeling of streptavidin using the modular method for affinity labeling (MoAL) that we developed based on a catalytic amide-forming reaction using 2-chloro-4,6-dimethoxy-1,3,5-triazine (CDMT) and a tertiary amine catalyst. The primary structures of avidin and streptavidin are significantly different from each other, and streptavidin does not possess an acidic amino acid ...
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متن کاملA convenient Simple Method for Synthesis of Meta-iodobenzylguanidine (MIBG)
Radioiodinated meta iodobenzylguanidine (MIBG) is one of the important radiopharmaceuticals in Nuclear Medicine. [123/131I]MIBG is used for imaging of Adrenal medulla, studying heart sympathetic nerves, treatment of pheochromacytoma and neuroblastoma. For clinical application, radioiodinated MIBG is prepared through isotopic exchange method, which includes replacement of radioactive iodine in a...
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ژورنال
عنوان ژورنال: Chemical Communications
سال: 2009
ISSN: 1359-7345,1364-548X
DOI: 10.1039/b912908a